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Involvement of KLF11 in Hepatic Glucose Metabolism in Mice via Suppressing of PEPCK-C Expression

BACKGROUND: Abnormal hepatic gluconeogenesis is related to hyperglycemia in mammals with insulin resistance. Despite the strong evidences linking Krüppel-like factor 11 (KLF11) gene mutations to development of Type 2 diabetes, the precise physiological functions of KLF11 in vivo remain largely unkno...

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Detalles Bibliográficos
Autores principales: Zhang, Huabing, Chen, Qi, Jiao, Tao, Cui, Anfang, Sun, Xiujing, Fang, Weijun, Xie, Liwei, Liu, Yang, Fang, Fude, Chang, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935883/
https://www.ncbi.nlm.nih.gov/pubmed/24586865
http://dx.doi.org/10.1371/journal.pone.0089552