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SnapShot-Seq: A Method for Extracting Genome-Wide, In Vivo mRNA Dynamics from a Single Total RNA Sample

mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are incompletely understood. Because the RNA intermediates in each of these steps have finite lifetimes, extensive mechanistic and dynamical information is encoded in total cellular RNA. Here we report the d...

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Detalles Bibliográficos
Autores principales: Gray, Jesse M., Harmin, David A., Boswell, Sarah A., Cloonan, Nicole, Mullen, Thomas E., Ling, Joseph J., Miller, Nimrod, Kuersten, Scott, Ma, Yong-Chao, McCarroll, Steven A., Grimmond, Sean M., Springer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935918/
https://www.ncbi.nlm.nih.gov/pubmed/24586954
http://dx.doi.org/10.1371/journal.pone.0089673