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SnapShot-Seq: A Method for Extracting Genome-Wide, In Vivo mRNA Dynamics from a Single Total RNA Sample
mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are incompletely understood. Because the RNA intermediates in each of these steps have finite lifetimes, extensive mechanistic and dynamical information is encoded in total cellular RNA. Here we report the d...
Autores principales: | Gray, Jesse M., Harmin, David A., Boswell, Sarah A., Cloonan, Nicole, Mullen, Thomas E., Ling, Joseph J., Miller, Nimrod, Kuersten, Scott, Ma, Yong-Chao, McCarroll, Steven A., Grimmond, Sean M., Springer, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935918/ https://www.ncbi.nlm.nih.gov/pubmed/24586954 http://dx.doi.org/10.1371/journal.pone.0089673 |
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