Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes

Recent studies have been successful at utilizing ectopic expression of transcription factors to generate induced cardiomyocytes (iCMs) from fibroblasts, albeit at a low frequency in vitro. This work investigates the influence of small molecules that have been previously reported to improve different...

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Detalles Bibliográficos
Autores principales: Ifkovits, Jamie L., Addis, Russell C., Epstein, Jonathan A., Gearhart, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935923/
https://www.ncbi.nlm.nih.gov/pubmed/24586958
http://dx.doi.org/10.1371/journal.pone.0089678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935923/
https://www.ncbi.nlm.nih.gov/pubmed/24586958
http://dx.doi.org/10.1371/journal.pone.0089678

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