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Inhibition of TGFβ Signaling Increases Direct Conversion of Fibroblasts to Induced Cardiomyocytes
Recent studies have been successful at utilizing ectopic expression of transcription factors to generate induced cardiomyocytes (iCMs) from fibroblasts, albeit at a low frequency in vitro. This work investigates the influence of small molecules that have been previously reported to improve different...
Autores principales: | Ifkovits, Jamie L., Addis, Russell C., Epstein, Jonathan A., Gearhart, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935923/ https://www.ncbi.nlm.nih.gov/pubmed/24586958 http://dx.doi.org/10.1371/journal.pone.0089678 |
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