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Critical Role of Interferon-α Constitutively Produced in Human Hepatocytes in Response to RNA Virus Infection

Several viruses are known to infect human liver and cause the hepatitis, but the interferon (IFN) response, a first-line defense against viral infection, of virus-infected hepatocytes is not clearly defined yet. We investigated innate immune system against RNA viral infection in immortalized human h...

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Detalles Bibliográficos
Autores principales: Tsugawa, Yoji, Kato, Hiroki, Fujita, Takashi, Shimotohno, Kunitada, Hijikata, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935935/
https://www.ncbi.nlm.nih.gov/pubmed/24587086
http://dx.doi.org/10.1371/journal.pone.0089869