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Critical Role of Interferon-α Constitutively Produced in Human Hepatocytes in Response to RNA Virus Infection
Several viruses are known to infect human liver and cause the hepatitis, but the interferon (IFN) response, a first-line defense against viral infection, of virus-infected hepatocytes is not clearly defined yet. We investigated innate immune system against RNA viral infection in immortalized human h...
Autores principales: | Tsugawa, Yoji, Kato, Hiroki, Fujita, Takashi, Shimotohno, Kunitada, Hijikata, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935935/ https://www.ncbi.nlm.nih.gov/pubmed/24587086 http://dx.doi.org/10.1371/journal.pone.0089869 |
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