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Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice
The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Aβ) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing and microvascular Aβ deposition was defined using quantitative label-free shotgun...
Autores principales: | Searcy, James L., Le Bihan, Thierry, Salvadores, Natalia, McCulloch, James, Horsburgh, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935958/ https://www.ncbi.nlm.nih.gov/pubmed/24587158 http://dx.doi.org/10.1371/journal.pone.0089970 |
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