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Metronidazole or Cotrimoxazole Therapy Is Associated with a Decrease in Intestinal Bioavailability of Common Antiretroviral Drugs

Metronidazole (MTZ) and Cotrimoxazole (CTX) are used in HIV/AIDS patients eligible for antiretroviral treatment. The objective of this animal study was to determine whether pre-treatment with antibiotics affects the intestinal bioavailability of Atazanavir (ATV) and Ritonavir (RTV). After oral admin...

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Detalles Bibliográficos
Autores principales: Dossou-Yovo, Flore, Mamadou, Godefroy, Soudy, Imar Djibrine, Limas-Nzouzi, Nicolas, Miantezila, Joe, Desjeux, Jehan-François, Eto, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935968/
https://www.ncbi.nlm.nih.gov/pubmed/24587140
http://dx.doi.org/10.1371/journal.pone.0089943