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Ulinastatin Preconditioning Attenuates Inflammatory Reaction of Hepatic Ischemia Reperfusion Injury in Rats via High Mobility Group Box 1(HMGB1) Inhibition

Objective It has been found that ulinastatin (UTI) can attenuate hepatic injury in a rat model of ischemia reperfusion (IR), but the specific mechanism is unclear. This study aims to investigate possible pathomechanism of ulinastatin in reducing the inflammatory response after hepatic IR. Methods A...

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Detalles Bibliográficos
Autores principales: Tong, Ying, Tang, Zhaohui, Yang, Tian, Yang, Yuting, Yang, Liqun, Shen, Weixing, Chen, Weixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936027/
https://www.ncbi.nlm.nih.gov/pubmed/24578610
http://dx.doi.org/10.7150/ijms.7861