Interferon β protects against lethal endotoxic and septic shock through SIRT1 upregulation

Lipopolysaccharide (LPS), an endotoxin derived from gram-negative bacteria, promotes the secretion of proinflammatory cytokines and mediates endotoxemia through activation of mitogen activated protein kinases, NF-κB, and interferon regulatory factor-3. Silent information regulator transcript-1 (SIRT...

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Detalles Bibliográficos
Autores principales: Yoo, Chae-Hwa, Yeom, Ji-Hyun, Heo, Jin-Ju, Song, Eun-Kyung, Lee, Sang-Il, Han, Myung-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936230/
https://www.ncbi.nlm.nih.gov/pubmed/24573134
http://dx.doi.org/10.1038/srep04220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936230/
https://www.ncbi.nlm.nih.gov/pubmed/24573134
http://dx.doi.org/10.1038/srep04220

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