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Formulation and Evaluation of Irinotecan Suppository for Rectal Administration

Irinotecan suppository was prepared using the moulding method with a homogeneous blend. A sensitive and specific fluorescence method was developed and validated for the determination of irinotecan in plasma using HPLC. The pharmacokinetics of intravenous administered and rectal administered in rabbi...

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Detalles Bibliográficos
Autores principales: Feng, Haiyang, Zhu, Yuping, Li, Dechuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936431/
https://www.ncbi.nlm.nih.gov/pubmed/24596626
http://dx.doi.org/10.4062/biomolther.2013.087