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PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity
Diabetes is a multi-organ disease and diabetic cardiomyopathy can result in heart failure, which is a leading cause of morbidity and mortality in diabetic patients. In the liver, insulin resistance contributes to hyperglycaemia and hyperlipidaemia, which further worsens the metabolic profile. Defect...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936489/ https://www.ncbi.nlm.nih.gov/pubmed/24408966 http://dx.doi.org/10.1002/emmm.201303183 |