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Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data
Many studies have identified binding preferences for transcription factors (TFs), but few have yielded predictive models of how combinations of transcription factor binding sites generate specific levels of gene expression. Synthetic promoters have emerged as powerful tools for generating quantitati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936720/ https://www.ncbi.nlm.nih.gov/pubmed/24288374 http://dx.doi.org/10.1093/nar/gkt1230 |