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DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors
DNA transposon-based vectors have emerged as gene vehicles with a wide biomedical and therapeutic potential. So far, genomic insertion of such vectors has relied on the co-delivery of genetic material encoding the gene-inserting transposase protein, raising concerns related to persistent expression,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936723/ https://www.ncbi.nlm.nih.gov/pubmed/24270790 http://dx.doi.org/10.1093/nar/gkt1163 |