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DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors

DNA transposon-based vectors have emerged as gene vehicles with a wide biomedical and therapeutic potential. So far, genomic insertion of such vectors has relied on the co-delivery of genetic material encoding the gene-inserting transposase protein, raising concerns related to persistent expression,...

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Detalles Bibliográficos
Autores principales: Cai, Yujia, Bak, Rasmus O., Krogh, Louise Bechmann, Staunstrup, Nicklas H., Moldt, Brian, Corydon, Thomas J., Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936723/
https://www.ncbi.nlm.nih.gov/pubmed/24270790
http://dx.doi.org/10.1093/nar/gkt1163