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Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
Most mitotic homologous recombination (HR) events proceed via a synthesis-dependent strand annealing mechanism to avoid crossing over, which may give rise to chromosomal rearrangements and loss of heterozygosity. The molecular mechanisms controlling HR sub-pathway choice are poorly understood. Here,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936725/ https://www.ncbi.nlm.nih.gov/pubmed/24319145 http://dx.doi.org/10.1093/nar/gkt1263 |