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The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes
The precise regulation of S-phase–specific genes is critical for cell proliferation. How the repressive chromatin configuration mediated by the retinoblastoma protein and repressor E2F factors changes at the G1/S transition to allow transcription activation is unclear. Here we show ChIP-on-chip stud...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936757/ https://www.ncbi.nlm.nih.gov/pubmed/24265227 http://dx.doi.org/10.1093/nar/gkt1161 |