Poly(A) RNA and Paip2 act as allosteric regulators of poly(A)-binding protein

When bound to the 3′ poly(A) tail of mRNA, poly(A)-binding protein (PABP) modulates mRNA translation and stability through its association with various proteins. By visualizing individual PABP molecules in real time, we found that PABP, containing four RNA recognition motifs (RRMs), adopts a conform...

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Detalles Bibliográficos
Autores principales: Lee, Seung Hwan, Oh, Jungsic, Park, Jonghyun, Paek, Ki Young, Rho, Sangchul, Jang, Sung Key, Lee, Jong–Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936760/
https://www.ncbi.nlm.nih.gov/pubmed/24293655
http://dx.doi.org/10.1093/nar/gkt1170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936760/
https://www.ncbi.nlm.nih.gov/pubmed/24293655
http://dx.doi.org/10.1093/nar/gkt1170

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