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Transcription factor abundance controlled by an auto-regulatory mechanism involving a transcription start site switch

A transcriptional feedback loop is the simplest and most direct means for a transcription factor to provide an increased stability of gene expression. In this work performed in human cells, we reveal a new negative auto-regulatory mechanism involving an alternative transcription start site (TSS) usa...

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Detalles Bibliográficos
Autores principales: Ngondo, Richard Patryk, Carbon, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936768/
https://www.ncbi.nlm.nih.gov/pubmed/24234445
http://dx.doi.org/10.1093/nar/gkt1136