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Collaboration between CpG sites is needed for stable somatic inheritance of DNA methylation states

Inheritance of 5-methyl cytosine modification of CpG (CG/CG) DNA sequences is needed to maintain early developmental decisions in vertebrates. The standard inheritance model treats CpGs as independent, with methylated CpGs maintained by efficient methylation of hemimethylated CpGs produced after DNA...

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Detalles Bibliográficos
Autores principales: Haerter, Jan O., Lövkvist, Cecilia, Dodd, Ian B., Sneppen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936770/
https://www.ncbi.nlm.nih.gov/pubmed/24288373
http://dx.doi.org/10.1093/nar/gkt1235