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Differential contribution of basic residues to HIV-1 nucleocapsid protein’s nucleic acid chaperone function and retroviral replication

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid (NC) protein contains 15 basic residues located throughout its 55-amino acid sequence, as well as one aromatic residue in each of its two CCHC-type zinc finger motifs. NC facilitates nucleic acid (NA) rearrangements via its chaperone activ...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Mitra, Mithun, Naufer, M. Nabuan, McCauley, Micah J., Gorelick, Robert J., Rouzina, Ioulia, Musier-Forsyth, Karin, Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936775/
https://www.ncbi.nlm.nih.gov/pubmed/24293648
http://dx.doi.org/10.1093/nar/gkt1227