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Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses

[Image: see text] The efficacious delivery of antigens to antigen-presenting cells (APCs), in particular, to dendritic cells (DCs), and their subsequent activation remains a significant challenge in the development of effective vaccines. This study highlights the potential of dissolving microneedle...

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Detalles Bibliográficos
Autores principales: Zaric, Marija, Lyubomska, Oksana, Touzelet, Olivier, Poux, Candice, Al-Zahrani, Sharifah, Fay, Francois, Wallace, Leah, Terhorst, Dorothea, Malissen, Bernard, Henri, Sandrine, Power, Ultan F., Scott, Christopher J., Donnelly, Ryan F., Kissenpfennig, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936823/
https://www.ncbi.nlm.nih.gov/pubmed/23373658
http://dx.doi.org/10.1021/nn304235j