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Piper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells

BACKGROUND: Nuclear factor-erythroid 2 p45 related factor 2 (Nrf2) is a primary transcription factor, protecting cells from oxidative stress by regulating a number of antioxidants and phase II detoxifying enzymes. Dietary components such as sulforaphane in broccoli and quercetin in onions have been...

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Detalles Bibliográficos
Autores principales: Wan Hasan, Wan Nuraini, Kwak, Mi-Kyoung, Makpol, Suzana, Ngah, Wan Zurinah Wan, Yusof, Yasmin Anum Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936848/
https://www.ncbi.nlm.nih.gov/pubmed/24559113
http://dx.doi.org/10.1186/1472-6882-14-72