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Quetiapine and aripiprazole signal differently to ERK, p90RSK and c-Fos in mouse frontal cortex and striatum: role of the EGF receptor

BACKGROUND: Signaling pathways outside dopamine D2 receptor antagonism may govern the variable clinical profile of antipsychotic drugs (APD) in schizophrenia. One postulated mechanism causal to APD action may regulate synaptic plasticity and neuronal connectivity via the extracellular signal-regulat...

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Detalles Bibliográficos
Autores principales: Pereira, Avril, Zhang, Betty, Malcolm, Peter, Sugiharto-Winarno, Anthony, Sundram, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936900/
https://www.ncbi.nlm.nih.gov/pubmed/24552586
http://dx.doi.org/10.1186/1471-2202-15-30