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Regulation of Myelination in the Central Nervous System by Nuclear Lamin B1 and Non-coding RNAs

Adult-onset autosomal dominant leukodystrophy (ADLD) is a progressive and fatal hereditary demyelination disorder characterized initially by autonomic dysfunction and loss of myelin in the central nervous system (CNS). Majority of ADLD is caused by a genomic duplication of the nuclear lamin B1 gene...

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Detalles Bibliográficos
Autores principales: Lin, Shu-Ting, Heng, Mary Y, Ptáček, Louis J, Fu, Ying-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937061/
https://www.ncbi.nlm.nih.gov/pubmed/24495672
http://dx.doi.org/10.1186/2047-9158-3-4