Cargando…

Sodium glucose cotransporter 1 ligand BLF501 as a novel tool for management of gastrointestinal mucositis

BACKGROUND: Recent studies demonstrated that engagement of sodium glucose transporter 1 (SGLT-1) by orally administered D-glucose protects the intestinal mucosa from lipopolysaccharide (LPS)-induced injury. We tested whether SGLT-1 engagement might protect the intestinal mucosa from doxorubicin (DXR...

Descripción completa

Detalles Bibliográficos
Autores principales: Cardani, Diego, Sardi, Claudia, La Ferla, Barbara, D’Orazio, Giuseppe, Sommariva, Michele, Marcucci, Fabrizio, Olivero, Daniela, Tagliabue, Elda, Koepsell, Hermann, Nicotra, Francesco, Balsari, Andrea, Rumio, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937063/
https://www.ncbi.nlm.nih.gov/pubmed/24495286
http://dx.doi.org/10.1186/1476-4598-13-23