CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis

The expression of the forkhead transcription factor checkpoint suppressor 1 (CHES1), also known as FOXN3, is reduced in many types of cancers. We show here that CHES1 decreases protein synthesis and cell proliferation in tumor cell lines but not in normal fibroblasts. Conversely, short hairpin RNA–m...

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Detalles Bibliográficos
Autores principales: Huot, Geneviève, Vernier, Mathieu, Bourdeau, Véronique, Doucet, Laurent, Saint-Germain, Emmanuelle, Gaumont-Leclerc, Marie-France, Moro, Alejandro, Ferbeyre, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937083/
https://www.ncbi.nlm.nih.gov/pubmed/24403608
http://dx.doi.org/10.1091/mbc.E13-02-0110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937083/
https://www.ncbi.nlm.nih.gov/pubmed/24403608
http://dx.doi.org/10.1091/mbc.E13-02-0110

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