Functional genomic screen identifies novel mediators of collagen uptake

Tissue fibrosis occurs when matrix production outpaces matrix degradation. Degradation of collagen, the main component of fibrotic tissue, is mediated through an extracellular proteolytic pathway and intracellular pathway of cellular uptake and lysosomal digestion. Recent studies demonstrate that di...

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Detalles Bibliográficos
Autores principales: Lee, Ting-Hein, McKleroy, William, Khalifeh-Soltani, Amin, Sakuma, Stephen, Lazarev, Stanislav, Riento, Kirsi, Nishimura, Stephen L., Nichols, Ben J., Atabai, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937085/
https://www.ncbi.nlm.nih.gov/pubmed/24403604
http://dx.doi.org/10.1091/mbc.E13-07-0382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937085/
https://www.ncbi.nlm.nih.gov/pubmed/24403604
http://dx.doi.org/10.1091/mbc.E13-07-0382

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