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The spindle and kinetochore–associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit

The spindle and kinetochore–associated (Ska) protein complex is a heterotrimeric complex required for timely anaphase onset. The major phenotypes seen after small interfering RNA–mediated depletion of Ska are transient alignment defects followed by metaphase arrest that ultimately results in cohesio...

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Detalles Bibliográficos
Autores principales: Sivakumar, Sushama, Daum, John R., Tipton, Aaron R., Rankin, Susannah, Gorbsky, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937086/
https://www.ncbi.nlm.nih.gov/pubmed/24403607
http://dx.doi.org/10.1091/mbc.E13-07-0421