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The spindle and kinetochore–associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit
The spindle and kinetochore–associated (Ska) protein complex is a heterotrimeric complex required for timely anaphase onset. The major phenotypes seen after small interfering RNA–mediated depletion of Ska are transient alignment defects followed by metaphase arrest that ultimately results in cohesio...
Autores principales: | Sivakumar, Sushama, Daum, John R., Tipton, Aaron R., Rankin, Susannah, Gorbsky, Gary J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937086/ https://www.ncbi.nlm.nih.gov/pubmed/24403607 http://dx.doi.org/10.1091/mbc.E13-07-0421 |
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