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Cell cycle–regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation

Accurate and efficient separation of sister chromatids during anaphase is critical for faithful cell division. It has been proposed that cortical dynein–generated pulling forces on astral microtubules contribute to anaphase spindle elongation and chromosome separation. In mammalian cells, however, d...

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Detalles Bibliográficos
Autores principales: Zheng, Zhen, Wan, Qingwen, Meixiong, Gerry, Du, Quansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937087/
https://www.ncbi.nlm.nih.gov/pubmed/24371089
http://dx.doi.org/10.1091/mbc.E13-08-0474