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A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity
The timely delivery of membranous organelles and macromolecules to specific locations within the majority of eukaryotic cells depends on microtubule-based transport. Here we describe a screening method to identify mutations that have a critical effect on intracellular transport and its regulation us...
Autores principales: | Tan, Kaeling, Roberts, Anthony J., Chonofsky, Mark, Egan, Martin J., Reck-Peterson, Samara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937092/ https://www.ncbi.nlm.nih.gov/pubmed/24403603 http://dx.doi.org/10.1091/mbc.E13-09-0557 |
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