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A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis

Lipid droplet (LD) utilization is an important cellular activity that regulates energy balance and release of lipid second messengers. Because fatty acids exhibit both beneficial and toxic properties, their release from LDs must be controlled. Here we demonstrate that yeast Sfh3, an unusual Sec14-li...

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Detalles Bibliográficos
Autores principales: Ren, Jihui, Pei-Chen Lin, Coney, Pathak, Manish C., Temple, Brenda R. S., Nile, Aaron H., Mousley, Carl J., Duncan, Mara C., Eckert, Debra M., Leiker, Thomas J., Ivanova, Pavlina T., Myers, David S., Murphy, Robert C., Brown, H. Alex, Verdaasdonk, Jolien, Bloom, Kerry S., Ortlund, Eric A., Neiman, Aaron M., Bankaitis, Vytas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937096/
https://www.ncbi.nlm.nih.gov/pubmed/24403601
http://dx.doi.org/10.1091/mbc.E13-11-0634