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A Combination of Transcriptional and MicroRNA Regulation Improves the Stability of the Relative Concentrations of Target Genes

It is well known that, under suitable conditions, microRNAs are able to fine tune the relative concentration of their targets to any desired value. We show that this function is particularly effective when one of the targets is a Transcription Factor (TF) which regulates the other targets. This comb...

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Detalles Bibliográficos
Autores principales: Riba, Andrea, Bosia, Carla, El Baroudi, Mariama, Ollino, Laura, Caselle, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937125/
https://www.ncbi.nlm.nih.gov/pubmed/24586138
http://dx.doi.org/10.1371/journal.pcbi.1003490