Analysis of Meiosis in SUN1 Deficient Mice Reveals a Distinct Role of SUN2 in Mammalian Meiotic LINC Complex Formation and Function

LINC complexes are evolutionarily conserved nuclear envelope bridges, composed of SUN (Sad-1/UNC-84) and KASH (Klarsicht/ANC-1/Syne/homology) domain proteins. They are crucial for nuclear positioning and nuclear shape determination, and also mediate nuclear envelope (NE) attachment of meiotic telome...

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Detalles Bibliográficos
Autores principales: Link, Jana, Leubner, Monika, Schmitt, Johannes, Göb, Eva, Benavente, Ricardo, Jeang, Kuan-Teh, Xu, Rener, Alsheimer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937131/
https://www.ncbi.nlm.nih.gov/pubmed/24586178
http://dx.doi.org/10.1371/journal.pgen.1004099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937131/
https://www.ncbi.nlm.nih.gov/pubmed/24586178
http://dx.doi.org/10.1371/journal.pgen.1004099

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