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Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoimmune hyperthyroidism (Graves' disease)....

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Autores principales: Medici, Marco, Porcu, Eleonora, Pistis, Giorgio, Teumer, Alexander, Brown, Suzanne J., Jensen, Richard A., Rawal, Rajesh, Roef, Greet L., Plantinga, Theo S., Vermeulen, Sita H., Lahti, Jari, Simmonds, Matthew J., Husemoen, Lise Lotte N., Freathy, Rachel M., Shields, Beverley M., Pietzner, Diana, Nagy, Rebecca, Broer, Linda, Chaker, Layal, Korevaar, Tim I. M., Plia, Maria Grazia, Sala, Cinzia, Völker, Uwe, Richards, J. Brent, Sweep, Fred C., Gieger, Christian, Corre, Tanguy, Kajantie, Eero, Thuesen, Betina, Taes, Youri E., Visser, W. Edward, Hattersley, Andrew T., Kratzsch, Jürgen, Hamilton, Alexander, Li, Wei, Homuth, Georg, Lobina, Monia, Mariotti, Stefano, Soranzo, Nicole, Cocca, Massimiliano, Nauck, Matthias, Spielhagen, Christin, Ross, Alec, Arnold, Alice, van de Bunt, Martijn, Liyanarachchi, Sandya, Heier, Margit, Grabe, Hans Jörgen, Masciullo, Corrado, Galesloot, Tessel E., Lim, Ee M., Reischl, Eva, Leedman, Peter J., Lai, Sandra, Delitala, Alessandro, Bremner, Alexandra P., Philips, David I. W., Beilby, John P., Mulas, Antonella, Vocale, Matteo, Abecasis, Goncalo, Forsen, Tom, James, Alan, Widen, Elisabeth, Hui, Jennie, Prokisch, Holger, Rietzschel, Ernst E., Palotie, Aarno, Feddema, Peter, Fletcher, Stephen J., Schramm, Katharina, Rotter, Jerome I., Kluttig, Alexander, Radke, Dörte, Traglia, Michela, Surdulescu, Gabriela L., He, Huiling, Franklyn, Jayne A., Tiller, Daniel, Vaidya, Bijay, de Meyer, Tim, Jørgensen, Torben, Eriksson, Johan G., O'Leary, Peter C., Wichmann, Eric, Hermus, Ad R., Psaty, Bruce M., Ittermann, Till, Hofman, Albert, Bosi, Emanuele, Schlessinger, David, Wallaschofski, Henri, Pirastu, Nicola, Aulchenko, Yurii S., de la Chapelle, Albert, Netea-Maier, Romana T., Gough, Stephen C. L., Meyer zu Schwabedissen, Henriette, Frayling, Timothy M., Kaufman, Jean-Marc, Linneberg, Allan, Räikkönen, Katri, Smit, Johannes W. A., Kiemeney, Lambertus A., Rivadeneira, Fernando, Uitterlinden, André G., Walsh, John P., Meisinger, Christa, den Heijer, Martin, Visser, Theo J., Spector, Timothy D., Wilson, Scott G., Völzke, Henry, Cappola, Anne, Toniolo, Daniela, Sanna, Serena, Naitza, Silvia, Peeters, Robin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134/
https://www.ncbi.nlm.nih.gov/pubmed/24586183
http://dx.doi.org/10.1371/journal.pgen.1004123