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Cascades of Genetic Instability Resulting from Compromised Break-Induced Replication

Break-induced replication (BIR) is a mechanism to repair double-strand breaks (DSBs) that possess only a single end that can find homology in the genome. This situation can result from the collapse of replication forks or telomere erosion. BIR frequently produces various genetic instabilities includ...

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Detalles Bibliográficos
Autores principales: Vasan, Soumini, Deem, Angela, Ramakrishnan, Sreejith, Argueso, Juan Lucas, Malkova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937135/
https://www.ncbi.nlm.nih.gov/pubmed/24586181
http://dx.doi.org/10.1371/journal.pgen.1004119