Cargando…

Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

BACKGROUND: Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. The objective of this randomized, double-blind, placebo-controlled, phase I trial was to determine the safety of intravenously infused ascorbic acid in patients wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fowler, Alpha A, Syed, Aamer A, Knowlson, Shelley, Sculthorpe, Robin, Farthing, Don, DeWilde, Christine, Farthing, Christine A, Larus, Terri L, Martin, Erika, Brophy, Donald F, Gupta, Seema, Fisher, Bernard J, Natarajan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937164/
https://www.ncbi.nlm.nih.gov/pubmed/24484547
http://dx.doi.org/10.1186/1479-5876-12-32