DNA polymerase preference determines PCR priming efficiency

BACKGROUND: Polymerase chain reaction (PCR) is one of the most important developments in modern biotechnology. However, PCR is known to introduce biases, especially during multiplex reactions. Recent studies have implicated the DNA polymerase as the primary source of bias, particularly initiation of...

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Detalles Bibliográficos
Autores principales: Pan, Wenjing, Byrne-Steele, Miranda, Wang, Chunlin, Lu, Stanley, Clemmons, Scott, Zahorchak, Robert J, Han, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937175/
https://www.ncbi.nlm.nih.gov/pubmed/24479830
http://dx.doi.org/10.1186/1472-6750-14-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937175/
https://www.ncbi.nlm.nih.gov/pubmed/24479830
http://dx.doi.org/10.1186/1472-6750-14-10

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