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Isotype-specific inhibition of the phosphatidylinositol-3-kinase pathway in hematologic malignancies

In the last decade, the advent of biological targeted therapies has revolutionized the management of several types of cancer, especially in the realm of hematologic malignancies. One of these pathways, and the center of this review, is the phosphatidylinositol-3-kinase (PI3K) pathway. The PI3K pathw...

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Detalles Bibliográficos
Autores principales: Castillo, Jorge J, Iyengar, Meera, Kuritzky, Benjamin, Bishop, Kenneth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937185/
https://www.ncbi.nlm.nih.gov/pubmed/24591840
http://dx.doi.org/10.2147/OTT.S34641