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Mammalian E-type Cyclins Control Chromosome Pairing, Telomere Stability and CDK2 Localization in Male Meiosis

Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type cyclins during spermatogenesis, we characterized their expression patterns and produced additional deletions of C...

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Detalles Bibliográficos
Autores principales: Martinerie, Laetitia, Manterola, Marcia, Chung, Sanny S. W., Panigrahi, Sunil K., Weisbach, Melissa, Vasileva, Ana, Geng, Yan, Sicinski, Peter, Wolgemuth, Debra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937215/
https://www.ncbi.nlm.nih.gov/pubmed/24586195
http://dx.doi.org/10.1371/journal.pgen.1004165