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Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection

One of the hallmarks of adaptive immunity is the development of a long-term pathogen specific memory response. While persistent memory T cells certainly impact the immune response during a secondary challenge, their role in unrelated infections is less clear. To address this issue, we utilized lymph...

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Detalles Bibliográficos
Autores principales: Crosby, Erika J., Goldschmidt, Michael H., Wherry, E. John, Scott, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937277/
https://www.ncbi.nlm.nih.gov/pubmed/24586170
http://dx.doi.org/10.1371/journal.ppat.1003970