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Anticancer Compound Plumbagin and Its Molecular Targets: A Structural Insight into the Inhibitory Mechanisms Using Computational Approaches

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a naphthoquinone derivative from the roots of plant Plumbago zeylanica and belongs to one of the largest and diverse groups of plant metabolites. The anticancer and antiproliferative activities of plumbagin have been observed in animal models as w...

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Detalles Bibliográficos
Autores principales: Jamal, Mohammad S., Parveen, Shadma, Beg, Mohd A., Suhail, Mohd, Chaudhary, Adeel G. A., Damanhouri, Ghazi A., Abuzenadah, Adel M., Rehan, Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937309/
https://www.ncbi.nlm.nih.gov/pubmed/24586269
http://dx.doi.org/10.1371/journal.pone.0087309