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Randomized Pharmacokinetic Study Comparing Subcutaneous and Intravenous Palonosetron in Cancer Patients Treated with Platinum Based Chemotherapy

BACKGROUND: Palonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though it could have useful clinical applications....

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Detalles Bibliográficos
Autores principales: Sadaba, Belen, del Barrio, Anabel, Campanero, Miguel Angel, Azanza, Jose Ramon, Gomez-Guiu, Almudena, Lopez-Picazo, Jose Maria, Algarra, Salvador Martin, Grimá, Francisco Guillén, Prieto, Maria Blanco, Perez-Gracia, Jose Luis, Gurpide, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937332/
https://www.ncbi.nlm.nih.gov/pubmed/24587006
http://dx.doi.org/10.1371/journal.pone.0089747