Gene Expression Alterations in the Cerebellum and Granule Neurons of Cstb(−/−) Mouse Are Associated with Early Synaptic Changes and Inflammation

Progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1) is an autosomal recessively inherited neurodegenerative disease, manifesting with myoclonus, seizures and ataxia, caused by mutations in the cystatin B (CSTB) gene. With the aim of understanding the molecular basis of pathogenetic eve...

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Detalles Bibliográficos
Autores principales: Joensuu, Tarja, Tegelberg, Saara, Reinmaa, Eva, Segerstråle, Mikael, Hakala, Paula, Pehkonen, Heidi, Korpi, Esa R., Tyynelä, Jaana, Taira, Tomi, Hovatta, Iiris, Kopra, Outi, Lehesjoki, Anna-Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937333/
https://www.ncbi.nlm.nih.gov/pubmed/24586687
http://dx.doi.org/10.1371/journal.pone.0089321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937333/
https://www.ncbi.nlm.nih.gov/pubmed/24586687
http://dx.doi.org/10.1371/journal.pone.0089321

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