Cargando…

Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging

BACKGROUND: Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase “immunosenesence” of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a marker of proliferative history. Whether chronic HIV infection causes similar effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Sulggi A., Sinclair, Elizabeth, Hatano, Hiroyu, Hsue, Priscilla Y., Epling, Lorrie, Hecht, Frederick M., Bangsberg, David R., Martin, Jeffrey N., McCune, Joseph M., Deeks, Steven G., Hunt, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937334/
https://www.ncbi.nlm.nih.gov/pubmed/24586783
http://dx.doi.org/10.1371/journal.pone.0089444