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Inferring the Temporal Order of Cancer Gene Mutations in Individual Tumor Samples

The temporal order of cancer gene mutations in tumors is essential for understanding and treating the disease. Existing methods are unable to infer the order of mutations that are identified at the same time in individual tumor samples, leaving the heterogeneity of the order unknown. Here, we show t...

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Detalles Bibliográficos
Autores principales: Guo, Jun, Guo, Hanliang, Wang, Zhanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937336/
https://www.ncbi.nlm.nih.gov/pubmed/24586626
http://dx.doi.org/10.1371/journal.pone.0089244