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Inferring the Temporal Order of Cancer Gene Mutations in Individual Tumor Samples
The temporal order of cancer gene mutations in tumors is essential for understanding and treating the disease. Existing methods are unable to infer the order of mutations that are identified at the same time in individual tumor samples, leaving the heterogeneity of the order unknown. Here, we show t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937336/ https://www.ncbi.nlm.nih.gov/pubmed/24586626 http://dx.doi.org/10.1371/journal.pone.0089244 |