A Force-Based, Parallel Assay for the Quantification of Protein-DNA Interactions

Analysis of transcription factor binding to DNA sequences is of utmost importance to understand the intricate regulatory mechanisms that underlie gene expression. Several techniques exist that quantify DNA-protein affinity, but they are either very time-consuming or suffer from possible misinterpret...

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Detalles Bibliográficos
Autores principales: Limmer, Katja, Pippig, Diana A., Aschenbrenner, Daniela, Gaub, Hermann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937344/
https://www.ncbi.nlm.nih.gov/pubmed/24586920
http://dx.doi.org/10.1371/journal.pone.0089626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937344/
https://www.ncbi.nlm.nih.gov/pubmed/24586920
http://dx.doi.org/10.1371/journal.pone.0089626

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