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Progressive Brain Damage, Synaptic Reorganization and NMDA Activation in a Model of Epileptogenic Cortical Dysplasia

Whether severe epilepsy could be a progressive disorder remains as yet unresolved. We previously demonstrated in a rat model of acquired focal cortical dysplasia, the methylazoxymethanol/pilocarpine - MAM/pilocarpine - rats, that the occurrence of status epilepticus (SE) and subsequent seizures fost...

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Detalles Bibliográficos
Autores principales: Colciaghi, Francesca, Finardi, Adele, Nobili, Paola, Locatelli, Denise, Spigolon, Giada, Battaglia, Giorgio Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937400/
https://www.ncbi.nlm.nih.gov/pubmed/24587109
http://dx.doi.org/10.1371/journal.pone.0089898